12 results
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Pain Eyes ... Subacute bacterial endocarditis ... system • Mitral ... - Bacterial endocarditis ... #pain #differential
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... Pain Rash ... infection Malar rash ... • Rheumatic fever ... #differential #
Infectious Joint Pain - Differential Diagnosis Algorithm 
Polyarticular Join Pain
 • Viral Myalgia
 • Viral Arthritis
Infectious Joint ... Pain - Differential ... Polyarticular Join ... PainViral ... Infection • Endocarditis
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
) General: Fever ... Photosensitivity, Butterfly rash ... of hip (rare), Arthritis ... lesions Abdominal pain ... #systemic #erythematosus
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... rashErythematous ... permanent alopecia Differential ... : • Joint pain ... • Libman-Sacks endocarditis
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis ... Differential Diagnosis ... • Rheumatic fever ... • Bacterial endocarditis ... Joint #pain #Differential
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Pain - Diagnostic ... acute rheumatic fever ... Chronic = RA, SLE ... #Joint #Pain #MSK ... approach #workup #differential
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
muscle weakness, rash ... , Fever, No muscle ... with temporal arteritis ... Detectable HIV viral ... Myopathies #myopathy #differential
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... pain (especially ... the face (many differential ... 9) Unexplained fever ... clues #system #erythematosus
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
vesicular eruption - Joints ... Coronary arteries - Fever ... mucositis - Rash ... Vasculitis: • Fevers ... vasculitis, and SLE