9 results
Primary and Secondary Causes of Mitral Regurgitation
Primary (organic) chronic mitral regurgitation:
 • Leaflet: Rheumatic fever, Infective
Leaflet: Rheumatic fever ... , Infective endocarditis ... cushion defects), Systemic ... cardiomyopathy - VA Joint ... Regurgitation #differential
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
(SLE) General: Fever ... Photosensitivity, Butterfly rash ... phenomenon (20%) Joints ... Pericarditis, Endocarditis ... #erythematosus
Extra-articular and Other Conditions Associated with Joint Pain

Eyes
  • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Subacute bacterial endocarditis ... • Mitral regurgitation ... - Bacterial endocarditis ... #pain #differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... Arthritis: • Joint ... • Libman-Sacks endocarditis ... to: Arthritis, Fever
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
) Inflammatory joint ... the face (many differential ... 9) Unexplained fever ... diagnosis #sle #clues #system ... #erythematosus
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Involves aortic and mitral ... night sweats, fever ... Vascular: • Systemic ... Marantic (NTBE) Differential ... underlying cause + Systemic
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
vesicular eruption - Joints ... Coronary arteries - Fever ... mucositis - Rash ... lupus erythematosus ... Vasculitis: • Fevers
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... ischemia • Skin: Erythematous ... vesicular eruption • Joints ... , mucositis • Rash ... Palpable purpura, joint
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
and Differential ... involves aortic and mitral ... night sweats, fever ... Vascular: • Systemic ... #Differential #