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diagnosis cardiology causes hematology joint algorithm anemia arthritis erythematosus hemolytic infectiousdiseases lupus management msk sle workup agglutinin approach clinical clues
Primary and Secondary Causes of Mitral Regurgitation Primary (organic) chronic mitral regurgitation: • Leaflet: Rheumatic fever, Infective
, Infective endocarditis ... , Infective endocarditis ... • Prosthetic valve ... annulus valve: ... Regurgitation #differential
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
Regions - Frequent Differential ... infective endocarditis ... • Abdominal pain ... endocarditis ... Returning #Traveler #differential
What's the Dx? • 29-year-old male • Transfer community hospital • Hypotension • Renal failure • Altered mental status.
• 29-year-old male ... demonstrate a mobile mitral ... young patient with fever ... Echocardiogram #PLAX #Infective ... #Endocarditis #
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 Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
infection • ... Subacute bacterial endocarditis ... infection, Amyloidosis ... #differential # ... diagnosis #rheumatology
Causes of Thrombocytopenia - Differential Diagnosis Framework Decreased Production: - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Thrombocytopenia - Differential ... quinine, etc) - Viral ... infiltration: malignancy, infection ... - Mechanical: valve ... replacement, endocarditis
Hemoptysis - Differential Diagnosis Framework Massive Hemoptysis: >150-300 mL in 24h Airway disease: • Bronchitis, Bronchiectasis, Malignancy
Hemoptysis - Differential ... Parenchyma: • Infection ... Kaposi's sarcoma • Rheumatologic ... • Valvular (Mitral ... regurgitation, Tricuspid endocarditis
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Involves aortic and mitral ... night sweats, fever ... Marantic (NTBE) Differential ... Paradoxical emboli via ASD ... Persistent bacteremia/fevers
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
infection, autoimmune ... Infection Clinical ... younger pts) Differential ... Symptoms: High fevers ... chills, flank pain
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... Agglutination - Cold ... mechanical cardiac valve ... inclusions - If infection ... bartonella (oroya fever
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
- Arthritis Differential ... By: - Chronic Infection ... • Rheumatic fever ... • Bacterial endocarditis ... #Differential #
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