11 results
Primary and Secondary Causes of Mitral Regurgitation
Primary (organic) chronic mitral regurgitation:
 • Leaflet: Rheumatic fever, Infective
and Secondary Causes ... Primary (organic) chronic ... inflammation (SLE ... cardiomyopathy - VA Joint ... Regurgitation #differential
Bradycardia - Differential Diagnosis Framework

BRADI Mnemonic
 • BRASH/Hyperkalemia
 • Reduced oxygen/Glucose/Temp
 • ACS
 • Drugs
 •
Bradycardia - Differential ... Endocarditis + ... • Post cardiac/Valve ... Autoimmune: • SLE ... #diagnosis #causes
Causes of Fever of Unknown Origin (FUO) - Differential Diagnosis Algorithm
Neoplasm:
• NHL
• Hodgkin's lymphoma
• Leukemia
• Solid
Causes of Fever ... Origin (FUO) - Differential ... Autoimmune: • SLE ... • Infectious endocarditis ... UnknownOrigin #FUO #Chronic
Causes of mitral stenosis
Rheumatic heart disease
 - Most common cause worldwide. Commissural fusion, thick MV leaflets
Causes of mitral ... Age-related changes, chronic ... leaflets/chordae) - SLE ... atrial myxoma)/ball valve ... #diagnosis #differential
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
acute rheumatic fever ... • Chronic - Think ... Like in this case ... = RA, SLE, psoriatic ... approach #workup #differential
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
Involves aortic and mitral ... • Autoimmune (SLE ... night sweats, fever ... Marantic (NTBE) Differential ... Persistent bacteremia/fevers
Approach to Joint Pain - Arthritis Differential Diagnosis Framework

Inflammatory Versus Noninflammatory Pain
 • Is it inflammatory
Pain - Arthritis Differential ... weeks) Can Be Caused ... • Rheumatic fever ... • Bacterial endocarditis ... arthritis • SLE
Causes of Primary and Functional Mitral Regurgitation (MR) 
Causes of primary mitral regurgitation
 - Rheumatic heart
Infective/marantic endocarditis ... Age-related changes, chronic ... valve - Secondary ... of coaptation point ... #Functional #Differential
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
and Differential ... involves aortic and mitral ... • Autoimmune (SLE ... night sweats, fever ... #Endocarditis #Differential
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
weight loss, and fever ... permanent alopecia Differential ... • Libman-Sacks endocarditis ... Cytopenias • Cardiac valve ... with Lupus: • Chronic