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Primary and Secondary Causes of Mitral Regurgitation Primary (organic) chronic mitral regurgitation: • Leaflet: Rheumatic fever, Infective
Leaflet: Rheumatic fever ... • Prosthetic valve ... annulus valve: ... cardiomyopathy - VA Joint ... Regurgitation #differential
Extra-articular and Other Conditions Associated with Joint Pain Eyes • Iritis or uveitis - Spondyloarthropathies, Sarcoidosis,
Associated with Joint ... Pain Eyes ... Subacute bacterial endocarditis ... - Bacterial endocarditis ... #pain #differential
Infectious Joint Pain - Differential Diagnosis Algorithm Polyarticular Join Pain • Viral Myalgia • Viral Arthritis
Infectious Joint ... Pain - Differential ... Polyarticular Join ... Pain • Viral ... Infection • Endocarditis
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Pain - Diagnostic ... acute rheumatic fever ... • Acute = Viral ... #Joint #Pain #MSK ... approach #workup #differential
Fever in Returning Travelers from Tropical Regions - Frequent Differential Diagnoses Medical History: • Skin exposure to
Regions - Frequent Differential ... infection, infective endocarditis ... • Abdominal pain ... mononucleosis, infective endocarditis ... Returning #Traveler #differential
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... • Rheumatic fever ... Viral Infections ... • Bacterial endocarditis ... #pain #Differential
Endocarditis Summary Who? Infectious: • Pre-existing valvular disease • Prosthetic valve • Congenital heart disease • IV substance use • IV catheter • Recent
Involves aortic and mitral ... night sweats, fever ... Marantic (NTBE) Differential ... Paradoxical emboli via ASD ... Persistent bacteremia/fevers
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
Rheumatica • Pain ... , Fever, No muscle ... Detectable HIV viral ... Diffuse muscle pain ... Myopathies #myopathy #differential
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
(SLE) General: Fever ... phenomenon (20%) Joints ... Pericarditis, Endocarditis ... , Aortic valve lesions ... Abdominal pain
Leg Pain - Differential Diagnosis Framework Bone/Joint Causes of Leg Pain: • Fracture • Arthritis • Gout/pseudogout
Leg Pain - Differential ... Framework Bone/Joint ... sarcoma • Legg-Calve-Perthes ... - Fever/chills ... differential #diagnosis
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