8 results
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
alkalosis • Kidney ... Cl- outside the kidneys ... in the proximal tubule ... urine #Algorithm #nephrology ... #differential #diagnosis
Generalized Weakness - Differential Diagnosis Framework
"l feel weak":
 • Infectious: Influenza, EBV, PNA, Bacteremia, Sepsis
 •
- Differential Diagnosis ... Bacteremia, Sepsis • Kidneys ... : CKD, ESRD • CV ... chemo), EtOH, Rhabdomyolysis ... #causes #neurology
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
Inherited Defects in Kidney ... Tubule Epithelial ... Inherited #Defects #Kidney ... #Nephrology #Diagnosis ... #Differential #Table
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
in the distal tubule ... → Hypokalemia Metabolic ... Contraction → ↑ Renin ↑ Ca ... Pathophysiology #nephrology ... #diagnosis
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary

Causes of Rhabdomyolysis:
 • Trauma:
	- Immobilization
	- Crush injury
	- Compartment
Differential Diagnosis ... Heat stroke - Metabolic ... nephrotoxicity to kidney ... per day until stable ... causes #treatment #nephrology
Rhabdomyolysis - Differential Diagnosis Framework
Rhabdomyolysis = Destruction of skeletal muscle with leakage of contents into circulation.
Rhabdomyolysis - ... Glycogenolysis, Lipid metabolism ... malignant syndrome • Metabolic ... #Causes #nephrology ... #table
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
resistance • Metabolic ... disequilibrium syndrome • Diagnosis ... insipidus • Kidney ... Excretion #Diuresis #Nephrology ... #Medications #Table
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
distal convoluted tubule ... Hypochloremic metabolic ... • Seizures • Rhabdomyolysis ... Gitelman #Syndrome #diagnosis ... #nephrology #management