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diagnosis management symptoms differential erythematosus hematology lupus sle criteria disease oncology arteritis behcet behcets chronic cll comatose cryofibrinogenemia cryoglobulinemia cryoglobulins
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
• Cogan Syndrome ... purpura: strong sign ... retinopathy Lab Tests ... differential #diagnosis #rheumatology ... #classification
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... skin injury) • Neurologic ... (Clinical Dx). ... diagnosis #management #signs ... #symptoms #rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Butterfly rash, Vasculitis ... Demyelinating syndromes ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
Uveitis or retinal vasculitis ... Abnormal pathergy test ... Most Common Clinical ... uveitis, retinal vasculitis ... Diagnosis #criteria #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
activate the immune system ... : • Clinical triad ... disorder (e.g. systemic ... diagnosis #types #classification ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... affects the skin, neurologic ... cognitive impairment, neurologic ... • Cogan syndrome ... Differential #Diagnosis #Rheumatology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
EULAR/ACR Classification ... Criteria for Systemic ... Erythematosus Clinical ... least 2 joints • Neurologic ... Erythematosus #diagnosis #rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
et diutinum Neurologic ... Autoimmunity: • -MM/WM: Vasculitis ... Hypergammaglobulinemic macular ... Vasculitis) Autoantibodies ... Paraproteinemias #Hematology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... desaturation, Scotoma, Ocular ... autoimmune disorders (Systemic ... Manifestations #diagnosis #neurology ... #symptoms #signs
Giant cell arteritis (GCA) Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
inflammatory vasculitis ... , neurologic, and ... Diagnosis = clinical ... the “Chewing gum test ... them, but urgent rheumatology
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