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hematology management differential disease lupus signs systemic ana antinuclear sle vasculitis activation agglutinin anemia antibodies autoantibodies behcet behcets chronic classification
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... meningitis), MCC CNS symptoms ... (Clinical Dx). ... #signs #symptoms ... #rheumatology #
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
Behcet's Syndrome ... - Diagnosis Diagnostic ... Abnormal pathergy test ... Most Common Clinical ... #criteria #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... , macular, patchy ... Clinical Features ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
Optica (NMO) - Clinical ... desaturation, Scotoma, Ocular ... Systemic lupus erythematosus ... Manifestations #diagnosis ... #neurology #symptoms
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Clinical Presentation ... Fever is the main clinical ... Liver function tests ... #Diagnosis #Management ... #Hematology #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Demyelinating syndromes ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... likely it will be clinically ... SLE), Sjogren's Syndrome ... ANA #patterns #rheumatology ... #diagnosis #differential
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ischemia - Skin: erythematous ... systemic lupus erythematosus ... Presentation - Systemic Symptoms ... retinopathy Lab Tests ... #rheumatology #
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... Viral Infection Clinical ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
-15% If SLE is clinically ... suspected, tests ... SLE-SSc-AlM overlap syndromes ... Systemic #lupus #erythematosus ... #diagnosis #rheumatology
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