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management differential hematology signs neurology oncology algorithm pathophysiology treatment causes arthritis classification erythematosus infectiousdiseases lupus pulmonary syndromes workup infections leukemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... Viral Infection Clinical ... anemia • Cold ... test #cold # ... #hematology #diagnosis
Cold Urticaria Prevalence - 0.05% in the population Disease onset - Mostly 2nd to 4th decades of life Causes
clinical associations ... duration of symptoms ... angioedema Other symptoms ... #Urticaria #diagnosis ... #rheumatology #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... matter, spinal cord ... (Clinical Dx). ... #signs #symptoms ... #rheumatology #
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) - HELLP syndrome ... (e.g. primary cold ... , Copper and lead ... #hematology #anemia
Behcet's Syndrome - Diagnosis Diagnostic Criteria for Behget's Syndrome (International Study Group for Behget's Disease): • Recurrent,
- Diagnosis Diagnostic ... Abnormal pathergy test ... Most Common Clinical ... #disease #Diagnosis ... #criteria #rheumatology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Autoimmune: Warm AIHA, Cold ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell anemia ... Laboratory Tests ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
- Differential Diagnosis ... Myelodysplastic Syndromes ... Liver Function Tests ... • Rule out B12 and ... Liver Function Tests
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
SLICC SLE Diagnostic ... Erythematosus Clinical ... Criteria CLINICAL ... IMMUNOLOGIC CRITERIA - ANA ... #Diagnosis #Rheumatology
Acute Spinal Cord Injuries: Pathogenesis and clinical findings • Anterior Cord Syndrome -> Anterior spinal artery
clinical findings ... Syndrome ->Cord ... #diagnosis #pathophysiology ... #signs #symptoms ... #msk #orthopedics
Cubital Tunnel Syndrome: Pathogenesis and clinical findings • Paresthesia of 5th and medial half of 4th
clinical findings ... elbow flexion test ... #Diagnosis #pathophysiology ... #signs #symptoms ... #msk
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