12 results
Diabetes Combination Tablets - Estimated A1c Lowering 
Metformin + DPP4 
• Janumet (metformin + sitagliptin) 
•
Diabetes Combination ... + DPP4 • Janumet ... Combination #Tablets #Oral ... #DM2 #Pharmacology ... #Pills #Endocrinology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Summary Table ... Insulin Lifestyle ... modifications Metformin ... Sulfonylureas GLP ... events TZDs DPP
Mechanism of Action for Common Diabetes Medications

 • SGLT2i (Dapagliflozin)
 • TZD (Pioglitazone)
 • Biguanides (Metformin)
Action for Common Diabetes ... Meglitinides • GLP ... Receptor Agonists • DPP4i ... #Medications #pharmacology ... pathophysiology #endocrinology
Oral Hypoglycemics in Diabetes Management
1  INSULIN SENSITIZER
 • TZD 
     -
Oral Hypoglycemics ... Sensitivity - Metformin ... (Adlyxin) • DPP ... by inhibiting DPP ... #Management #pharmacology
Effects on body weight of various classes of type-2 diabetes medications.
 - Metformin - Weight Loss
- Metformin - ... Weight Loss ++ - GLP ... Weight Loss +++ - DPP ... Weight Gain ++ - Insulin ... weightgain #comparison #pharmacology
DPP-4 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits DPP-4 (dipeptidyl peptidase 4), which normally inactivates GLP-1
- Pharmacology ... Summary Mechanisms ... normally inactivates GLP ... #Summary #DM2 # ... diabetes #endocrinology
GLP-1 Agonists

Adlyxin (Lixisenatide) Daily
Bydureon (Exenatide ER) Weekly 
Ozempic (Semaglutide) Weekly 
Trulicity (Dulaglutide) Weekly 
Victoza (Liraglutide) Daily
medications for insulin ... There is an ORAL ... very similar to DPP4s ... #Pharmacology #Dosing ... #Endocrinology
Diabetes Mellitus Type 2 Inpatient Medication Guide

Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Diabetes Mellitus ... Sulfonylurea, TZD, DPP ... -4 inhibitor, GLP ... #Medications #pharmacology ... comparison #table #endocrinology
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... • Increases insulin-mediated ... Most effective oral ... Summary #DM2 #diabetes ... #endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary
Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
- Pharmacology ... Summary Mechanisms ... glucose-dependent insulin ... #Summary #DM2 # ... diabetes #endocrinology