18 results
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
of Drug-Induced Hyperkalemia ... • Direct renin inhibitor ... MunerMohamed1 #hyperkalemia ... differential #diagnosis #pathophysiology ... #pharmacology #
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
MECHANISM: Potassium Binder ... oral suspension DOSING ... ACE inhibitors, ... #KBinder #Hyperkalemia ... #Pharmacology
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
and sodium • Dosing ... magnesium • Dosing ... nonspecifically binds ... and calcium • Dosing ... #medications #pharmacology
Selective Serotonin Reuptake Inhibitors: Mechanisms and Side Effects
 • Serotonin Syndrome:
   - Autonomic Hyperactivity:
Serotonin Reuptake Inhibitors ... SSRIs #Serotonin #Inhibitors ... #Pathophysiology ... #Pharmacology # ... SideEffects #Psychiatry
Phosphate binders - quick reference chart of maximum daily dose. Most patients with CKD will require
Phosphate binders ... aluminum-based phosphate binder ... restricted due to hypercalcemia ... Hyperphosphatemia #Dose #Dosing ... #Pharmacology #
Serotonin-Norepinephrine Reuptake Inhibitors(SNRIs): Mechanisms and Side Effects

Withdrawal: Dizziness, Diarrhea, Insomnia, Nausea, Vomiting
Serotonin Syndrome - Potentially Life
Serotonin-Norepinephrine Reuptake Inhibitors ... SerotoninNorepinephrine #Inhibitors ... #Pathophysiology ... #Pharmacology # ... SideEffects #Psychiatry
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
Aldosterone Release: ACE inhibitors ... happypillsrx/ #Hyperkalemia ... #Pathophysiology ... #Pharmacology #
Initial treatment of renal bone disease and cinacalcet for secondary hyperparathyroidism
Phosphate binders reduce hyperphosphataemia and hyperparathyroidism.
hyperparathyroidism Phosphate binders ... Calcium-containing phosphate binders ... first-line treatments inhibits ... #Pharmacology #Pathophysiology
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Anticoagulants - Pathophysiology ... heparin (UFH): Inhibits ... allowing it to bind ... anticoagulant that inhibits ... #Pharmacology #Pathophysiology
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings
Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
mutation in CYP21A2 coding ... wasting crisis & hyperkalemia ... Milder forms present ... Complications: • Hyperkalemia ... #21HydroxylaseDeficiency #21OHD #pathophysiology