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Guide to Acute Kidney Injury (AKI)

What to ask/look for: 
 - HPI, PMH, full ROS
UOP/weights - Urine ... rhabdo/TLS) Causes ... Liano 1996) - ATN ... CKD— 13% (mostly ATN ... Diagnosis #Algorithm #Causes
Simplified Approach to Acute Kidney Injury (AKI)
1) IS THIS AN EMERGENCY? 
Is there a dialysis indication
Kidney Injury (AKI ... PROBLEM ~80% of AKI ... IMPROVEMENT If the urine ... CONSIDER INTRINSIC CAUSES ... etiologies due to ATN
Causes of Acute Kidney Injury - Differential Diagnosis Framework 
Pre-Renal
Post-Renal
Intrinsic Renal:
 • Tubules (ATN)
 • Glomerular:
Causes of Acute ... : • Tubules (ATN ... drtonydang @CMC_IM #AKI ... #KidneyInjury #Causes
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Kidney Injury - AKI ... osmolarity If cause ... of AKI remains ... Kidney #Injury #AKI ... Diagnosis #nephrology #causes
Mixed Cellular Casts on Urine Microscopy

Degenerating mixed cellular cast - brightfield, unstained - from patient with
Mixed Cellular Casts ... on Urine Microscopy ... pneumococcal sepsis and AKI ... #Cellular #Casts ... #clinical #Urine
Urinary Casts in the setting of renal disease
#Clinical #Nephro #Urine #Microscopy #Casts #Comparison #Chart #ATN #AIN
Urinary Casts in ... Clinical #Nephro #Urine ... #Microscopy #Casts ... Comparison #Chart #ATN
Acute Kidney Injury (AKI) - Differential Diagnosis Framework
Pre-Renal:
 • Hypovolemia, Cardiorenal, Distributive Shock, HRS, Hypercalcemia, Renal
Kidney Injury (AKI ... C3/C4, Other • ATN ... Medicine @SCVMCMed #AKI ... Diagnosis #nephrology #causes
Urinalysis & Urine Sodium 
Theophilus Protospatharius, a seventh-century physician who wrote the first manuscript focused exclusively
Urinalysis & Urine ... • Urinary casts ... Kidney Injury (AKI ... Tubular Necrosis (ATN ... #UNa #casts #glucosuria
Causes of Generalized Edema - Differential Diagnosis Algorithm
Overfill (Increased renal sodium retention, Urine Na > 40meq/L)
Causes of Generalized ... sodium retention, Urine ... • NSAlDs • AKI ... Diagnosis #Algorithm #Causes
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
Diagnostic Criteria HRS-AKI ... , Normal renal ultrasound ... Type 2) • HRS-AKD ... - No other cause ... - No other cause