16 results
Hypersensitivity: Summary
Type I Hypersensitivity:
 • Immunological Mediator: lgE
 • Immunological Target: Allergen Molecules
 • Ex: Antibiotic
Target: Antigen-Ab ... Dermatitis (ie. reaction ... #Allergic #Reactions ... #Types #Classification ... #Diagnosis #Definitions
Allergic Reaction Classification
Type 1 reaction: Acute anaphylactic reaction
Type 2 reaction: Cytotoxic reaction
Type 3 reaction: Immune complex
Type
Allergic Reaction ... Classification ... #Allergic #Reaction ... #Classification ... #diagnosis
Angioedema - Classification Diagnosis and Treatment
Types of Angioedema:
 • Acute allergic angioedema - Usually occurs with
Angioedema - Classification ... Diagnosis and Treatment ... drug reaction - ... #Angioedema #Classification ... #Types #Diagnosis
Hypersensitivity: Definitions
 • Type I - Production of lgE Abs that bind to harmless allergens and
reaction • Type ... An allergic reaction ... #Allergic #Reactions ... #Types #Classification ... #Diagnosis #Definitions
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?
- Differential Diagnosis ... syndrome, POEMS • Reaction ... post-splenectomy, Exercise, Allergic ... reactions Matthew ... #Differential #Diagnosis
Types of hypersensitivity reactions

Type I - lgE-Mediated, Within I Hour (Anaphylaxis)
Type II - IgG or IgM
hypersensitivity reactions ... hypersensitivity #reactions ... #Types #Classification ... #Allergy #Diagnosis
Rheumatoid Arthritis - 2020 ACR-EULAR Classification
≥ 6 of 10 points = definite RA
Joint Involvement:
2020 ACR-EULAR Classification ... negative anti CCP Ab ... Rheumatoid #Arthritis #diagnosis ... #EULAR #Classification ... #rheumatology
Hypersensitivity Types and Their Mechanisms
Type I - lgE - Soluble antigen
 - Allergen-specific lgE antibodies bind
When the specific allergen ... hay fever, food allergies ... , and drug allergies ... Hypersensitivity #Types #Classification ... #Diagnosis #Reactions
Basophilia - Differential Diagnosis Framework

Basophils < 1% of the total white blood cell count
Basophils function similarly
- Differential Diagnosis ... released during an allergic ... reaction or asthma ... Or Inflammatory Reactions ... #causes #hematology
Differential Diagnosis for Hemolytic Anemia
Intrinsic Causes:
 • Enzyme deficiencies ex. G6PD, pyruvate kinase 
 • Hemoglobinopathies
Differential Diagnosis ... • Transfusion reactions ... #Differential #Diagnosis ... #causes #classification ... #hematology