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management radiology treatment radiologyassistant signs sle symptoms syndrome erythematosus algorithm classification comparison disease hematology infections infectiousdiseases nephrology pneumonia summary systemic
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... associated with a +ANA ... , Interstitial Pulmonary ... #patterns #rheumatology ... #diagnosis #differential
Top 10 situations when to think about lupus 1) Inflammatory joint pain (especially in the wrists and
the face (many differential ... pleurisy (search ANA ... person (search ANA ... cytopenia (search ANA ... erythematosus #rheumatology
Pulmonary Renal Syndrome Definition: Diffuse alveolar hemorrhage + Glomerulonephritis Presentation (Pulmonary and renal manifestations can occur weeks apart):
symptomatology Differential ... Diagnosis for Pulmonary ... Complex: Systemic lupus ... , anti-GBM ab, ANA ... , anti-CCP • CXR
Hemoptysis - Differential Diagnosis Framework Airways: • Bronchitis • Bronchiectasis • Malignancy: Primary bronchogenic CA, Endobronchial
Diagnosis Framework ... , Lung abscess, ... Goodpastures, Lupus ... #Diagnosis #pulmonary ... #causes
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Myositis 4% - Lung ... Auto-Antibodies: - ANA ... (aPL) 30-45% Differential ... Diagnosis and Lupus ... #rheumatology
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm Idiopathic Interstitial Pneumonia • (UIP) Usual Interstitial Pneumonia
Causes of Interstitial ... Differential Diagnosis ... Arthritis, Systemic Lupus ... #Differential # ... Diagnosis #Algorithm
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... Workup: - ANA ... Positive in 60-80% of cases ... Management #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... Discontinuation of causal ... Workup: - ANA ... comparison #table #rheumatology ... #diagnosis #management
Rapidly Progressive Glomerulonephritis (RPGN) RPGN has three primary pathophysiologic causes differentiated by immunofluorescence Immune Complex Mediated (granular staining):
pathophysiologic causes ... Post-strep GN, Lupus ... With associated pulmonary ... #diagnosis #algorithm ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
findings (ANA, ... permanent alopecia Differential ... Diagnosis: • ANCA-associated ... Serositis Labs: • ANA ... antibodies • (-) ANA
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