17 results
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... vein: Budd-chiari syndrome ... • Gilbert's syndrome ... #algorithm #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation

Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
(LFTs) - Normal ... hepatocellular injury ... #Tests #LFTs #Laboratory ... Interpretation #diagnosis ... #hepatology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... Defects, Drugs, Liver ... Hypophostphatemia Laboratory ... Blood Smear ↑ abnormal ... #hematology
Commonly Observed Laboratory Findings in Hepatic / Liver Failure
 - Elevated conjugated and unconjugated bilirubin -
Commonly Observed Laboratory ... Findings in Hepatic / Liver ... the hepatorenal syndrome ... LiverFailure #Hepatic #Hepatology ... #Laboratory #Diagnosis
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
- If both are normal ... of ALP • Near normal ... • Gilbert's syndrome ... #chemistry #diagnosis ... #differential #Hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
injury, though ... upper limit of normal ... Necrosis) If mild laboratory ... regarding need for treatment ... #Management #Hepatology
Elevated Lactate Dehydrogenase (LDH) - Differential Diagnosis Framework

LDH is a cytoplasmic enzyme present in tissues throughout
- Differential Diagnosis ... RBCs, muscle, liver ... upon damage • Normal ... • Tumor lysis syndrome ... #Laboratory
Inherited Non-hemolytic Disorders of Hyperbilirubinemia 

== Disorders of Conjugation ==
Gilbert Syndrome:
 • 5-10% of the population
of about 30% of normal ... of hemolysis or liver ... injury ... Congenital #bilirubin #hepatology ... #diagnosis #gastroenterology
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Laboratory findings ... Multiple Sclerosis Treatment ... #management #neurology ... #treatment #MS
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
venipuncture sites Laboratory ... DIC • Severe Liver ... + Bleeding Treatment ... #Coagulation #diagnosis ... #causes #treatment