2196 results
Urine Microscopy - Kidney Stones and Crystals 

Uric Acid, Cystine, Hippurate, Cloth Fiber, Tyrosine, CaOx, CaP,
CaCO3, Struvite, Acyclovir ... Identification #Differential
Drug Induced Kidney Injury
 • Pre-Renal: NSAIDS, CNI, ACEI/ARB, IL-2 therapy, Diuretics CAR-T therapy
 • Osmotic
Methotrexate, Orlistat, Acyclovir ... #KidneyInjury #differential
Medications causing Acute Kidney Injury (AKI)
Prerenal:
 • Dehydration: Diuretics
 • Altered intrarenal autoregulation: ACEIs / ARBs,
Crystal nephropathy: Acyclovir ... #pharmacology #differential
Nephrolithiasis: Medications Associated with Renal Stones
 • Hypercalciuria: Furosemide, Topiramate, Vitamin D/Calcium, Glucocorticoids
 • Precipitation of
Sulfonamides, Acyclovir ... #pharmacology #differential
Types of Renal Calculi

Calcium oxalate
 - Interstitial apatite plaque, Low urine volume, Increased urinary calcium excretion,
2) Drugs - Acyclovir ... Renal #stones #differential
HSCT related renal disease - AKI and CKD
Acute Kidney Injury: Acute GvHD 2-4, Pre renal state,
Antibiotics, Sepsis, Acyclovir ... #disease #AKI #differential
The algorithm below shows how pre-test probability could be combined with various criteria to determine which
require empiric acyclovir ... The risk of acyclovir-induced ... favor the use of acyclovir ... -Acyclovir is nephrotoxic ... require empiric acyclovir
Acyclovir - Pharmacology Summary

 • Mechanism of Action: Nucleoside analog - selectively inhibits viral replication of
Acyclovir - Pharmacology ... TheIDtrivia #Acyclovir
Varicella (Chickenpox) - Crops of vesicles in various stages of healing 

Treatment 
• Healthy g 12
Immunocompromised or > 12: Acyclovir
Antibiotics and CNS Diffusion

1. Drugs with good CNS diffusion:

- Fluoroquinolones, Fluconazole, voriconazole, Rifampin, Oxazolidinones, Metronidazole

2. Drugs
β-lactam agents, Aciclovir