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differential lupus treatment erythematosus sle systemic ana hematology summary antibodies signs syndrome workup arthritis autoantibodies autoimmune classification druginduced oncology patterns
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... Kumfer @AnnKumfer #Antinuclear ... #patterns #rheumatology ... #diagnosis #differential
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
Associated Rheumatic Diseases ... connective tissue disease ... Kumfer @AnnKumfer #Antinuclear ... #patterns #rheumatology ... #diagnosis #differential
I’M DAMN SHARP - Lupus Diagnosis Mnemonic I Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid) M Malar Rash D
SHARP - Lupus Diagnosis ... Discoid Rash A Antinuclear ... Antibody (ANA) ... Arthritis R Renal Disease ... erythematosus #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... #Antinuclear #Antibody ... Antineutrophil #antibodies #diagnosis ... #rheumatology # ... diseases
Sensitivity of the ANA in Autoimmune & Nonrheumatic Disease #Diagnosis #Rheumatology #ANA #AntiNuclear #Antibodies #Sensitivity
Sensitivity of the ANA ... & Nonrheumatic Disease ... #Diagnosis #Rheumatology ... #ANA #AntiNuclear
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Erythematosus - Summary Antinuclear ... (ANA) - 95% - Initial ... #SLE #Summary #diagnosis ... #rheumatology # ... management
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... Retroperitoneum and aorta ... autoantibodies (antinuclear ... #diagnosis #management ... workup #treatment #rheumatology
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... Association with disease ... with auto-immune diseases ... erythematosus #diagnosis ... #rheumatology #
Hansen's Disease (Leprosy) • Transmission - not completely understood, ?nasal droplets • Symptoms appear ~5 years
nasal droplets • Symptoms ... few or absent AFB ... , and numerous AFB ... #Leprosy #diagnosis ... #management #treatment
Aortoenteric Fistula - Diagnosis and Management Summary Epidemiology: • Uncommon but life-threatening • Most common site of bowel connection
and Management ... Clinical Signs/Symptoms ... de novo between aorta ... compression of AAA ... or within the aorta
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