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differential treatment antibody disease lupus testing antibodies autoimmune cytoplasmic druginduced nuclear signs sle summary syndrome adult aih aortoenteric aosd arteritis
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
• Reticular/AMA ... PBC/SjS OS - AMA ... ARUPConsult @ARUPLabs #ANA ... #differential #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... : The ANA patterns ... #patterns #rheumatology ... #diagnosis #differential
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... @AnnKumfer #Antinuclear ... #Antibodies #ANA ... #patterns #rheumatology ... #diagnosis #differential
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Reticular/AMA: ... PBC/SjS OS • AMA ... ARUPConsult @ARUPLabs #ANA ... #differential #diagnosis ... #rheumatology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... ARUPConsult @ARUPLabs #ANA ... #Antinuclear #Antibody ... #differential #diagnosis ... #rheumatology
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Erythematosus - Summary Antinuclear ... (ANA) - 95% - Initial ... #SLE #Summary #diagnosis ... #rheumatology # ... management
Aortoenteric Fistula - Diagnosis and Management Summary Epidemiology: • Uncommon but life-threatening • Most common site of bowel connection
and Management ... Clinical Signs/Symptoms ... patient with known AAA ... compression of AAA ... known AAA (unrepaired
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
aorta • Head ... conventional imaging (aorta ... autoantibodies (antinuclear ... #management #phenotypes ... workup #treatment #rheumatology
Autoimmune Hepatitis Clinical Presentation - Highly variable clinical presentation, from subclinical disease to acute liver failure. -
- Symptoms of ... hepatocellular pattern ... though cholestatic pattern ... : Auto-Nuclear ANA ... #Management #Hepatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms ... Workup: - ANA ... Workup: - ANA ... comparison #table #rheumatology ... #diagnosis #management
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