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differential ana disease patterns treatment antibody lupus summary workup cytoplasmic druginduced hematology nuclear signs sle syndrome adult antibodies aortic aortoenteric
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Testing - Nuclear ... #Testing #Nuclear ... #differential #diagnosis ... #rheumatology
Antinuclear Antibody Testing Cytoplasmic Patterns Reticular/AMA: • PBC, SSc, PBC/SSc OS, PBC/SjS OS • AMA Speckled: •
Antinuclear Antibody ... Testing Cytoplasmic ... #Testing #Cytoplasmic ... #differential #diagnosis ... #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... context of other symptoms ... Kumfer @AnnKumfer #Antinuclear ... #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Erythematosus - Summary Antinuclear ... (ANA) - 95% - Initial ... #SLE #Summary #diagnosis ... #rheumatology # ... management
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
Retroperitoneum and aorta ... conventional imaging (aorta ... autoantibodies (antinuclear ... #management #phenotypes ... workup #treatment #rheumatology
Aortic Dissection - Diagnosis and Management Summary • HPI: sudden onset, "tearing" chest pain, radiation to
Aortic Dissection - Diagnosis ... sudden onset, "tearing ... concurrent stroke-like symptoms ... includes ascending aorta ... Aortic #Dissection #Diagnosis
Aortoenteric Fistula - Diagnosis and Management Summary Epidemiology: • Uncommon but life-threatening • Most common site of bowel connection
and Management ... Clinical Signs/Symptoms ... de novo between aorta ... compression of AAA ... or within the aorta
Atrial Fibrillation (A-Fib) Summary Symptoms: • Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope. Why? Cardiac: • Valvular heart
) Summary Symptoms ... possibly better: • Symptom ... Fibrillation - Testing ... (< 5% pts with afibb ... #diagnosis #management
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... erythematosus (SLE) - Antinuclear ... (to support a diagnosis ... laboratory #workup #diagnosis ... #testing #Rheumatology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... Testing - Nuclear ... #Testing #Nuclear ... #differential #diagnosis ... #rheumatology
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