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lupus disease druginduced erythematosus systemic treatment antibodies antinuclear behcet comparison dil diseases igg4 phenotypes polychondritis relapsing related signs summary symptoms
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and ... ANA - Non-specific ... Anti-mitochondrial (AMA ... diseases #diagnosis ... #table #rheumatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in ... Rheumatology • ... Lupus (SLE): ANA ... diagnosis #associations ... #table
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
searched for when ANA ... #Antinuclear #autoantibodies ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
: - ANA > ... of autoantibodies ... : - ANA > ... #rheumatology # ... diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... • Immunologic Workup ... : - ANA > ... Erythematosus #Diagnosis ... #rheumatology
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
aorta • Head ... serum lgE, no autoantibodies ... #management #phenotypes ... #workup #treatment ... #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Asia • HLA-B51 association ... Oral aphthae : SLE ... Glucocorticoids 5-ASA ... #management #signs ... #symptoms #rheumatology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
• Immunologic Workup ... : - ANA > ... of autoantibodies ... #diagnosis #treatment ... #management
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Large vessels (aorta ... cases such as: • SLE ... Nonspecific ↑ ESR, CRP, ANA ... Polychondritis #rheumatology ... #diagnosis #management
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