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ana antinuclear autoantibodies associations differential diseases lupus anca antineutrophil arthritis classification comparison disease druginduced erythematosus laboratory patterns polychondritis relapsing rheumatic
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
polyangiitis U1-RNP antibody ... disease Endomyseal antibody ... Associations #diseases #diagnosis ... #table #rheumatology ... #antibodies
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
• Lupus (SLE): ... ANA (anti-nuclear ... others (RNP, aPL antibodies ... #diagnosis #associations ... #table
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... Antineutrophil cytoplasmic antibodies ... in drug-induced SLE ... Antineutrophil #antibodies ... #diagnosis #rheumatology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers ... to antibodies against ... #Antinuclear #Antibodies ... #rheumatology #diagnosis
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... searched for when ANA ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... double-stranded DNA antibodies ... (to support a diagnosis ... laboratory #workup #diagnosis ... #testing #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Workup: - ANA ... Usual therapeutic management ... #comparison #table ... #rheumatology # ... diagnosis #management
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
< 30 years - Aorta ... branches • GCA: - Aorta ... C-ANCA) pattern: antibodies ... vasculitis, and SLE ... #rheumatology #
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
Large vessels (aorta ... cases such as: • SLE ... Anti-Matrilin-1 Ab ○ Antibodies ... Polychondritis #rheumatology ... #diagnosis #management
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