15 results
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear ... Antibody) and ANCA (Antineutrophil ... #Antinuclear #Antibody ... #ANCA #Antineutrophil ... antibodies #diagnosis #rheumatology
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Discoid Rash A Antinuclear ... Antibody (ANA) ... erythematosus #rheumatology
ANA Patterns and Associated Rheumatic Diseases:
 • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... Kumfer @AnnKumfer #Antinuclear ... #Antibodies #ANA ... #patterns #rheumatology
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody ... • Reticular/AMA ... PBC/SjS OS - AMA ... #Antinuclear #Antibody ... differential #diagnosis #rheumatology
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... (ANA) ANA or Anti-NucIear ... • +ANA can be seen ... Kumfer @AnnKumfer #Antinuclear ... #patterns #rheumatology
Sensitivity of the ANA in Autoimmune & Nonrheumatic Disease

#Diagnosis #Rheumatology #ANA #AntiNuclear #Antibodies #Sensitivity
Sensitivity of the ANA ... #Diagnosis #Rheumatology ... #ANA #AntiNuclear
Vasculitis - Break down based on vessel size 
Distribution of vessel involvement by large vessel vasculitis,
of vessel, from aorta ... left to right) aorta ... membrane; ANCA = antineutrophil ... #Diagnosis #Rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
Erythematosus - Summary Antinuclear ... (ANA) - 95% - Initial ... Summary #diagnosis #rheumatology
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... searched for when ANA ... Lupusreference #Antinuclear ... erythematosus #diagnosis #rheumatology ... #table #ANA
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
Retroperitoneum and aorta ... conventional imaging (aorta ... autoantibodies (antinuclear ... workup #treatment #rheumatology