13 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
pancreas, biliary, renal ... orientation, Biopsy ... orientation): ... management #phenotypes #workup ... #treatment #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
) - Diagnosis and ... • Immunologic Workup ... life-threatening • Treatment ... • Evolution: ... Management #Summary #rheumatology
Systemic Lupus Erythematosus - Summary
Antinuclear (ANA) - 95% - Initial screening test
Anti-dsDNA - 50%
 • Associated
severe disease & renal ... • Specific for SLE ... severe disease Treatment ... #Summary #diagnosis ... #rheumatology #
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... life-threatening • Treatment ... comparison #table #rheumatology ... #diagnosis #management
Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)
delta/delta) to see ... Ketoacidosis, Renal ... loss of bicarb, Renal ... GI loss of H+, Renal ... #workup #Differential
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
in 10 to 40% of SLE ... or 0.5 g/day → renal ... histological evaluation ... Nephritis #Management #treatment ... #management #rheumatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura

Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... activity is the diagnostic ... available for rapid diagnosis ... the presence of renal ... #Workup #Hematology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
post-hypothermia • ↓ Renal ... Excretion: - Renal ... reabsorption) Workup ... 15 suggests ↓ renal ... and Elimination (see
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
❹ Call for MH treatment ... COMPLICATIONS AND OUTLINE TREATMENTS ... ); may require renal ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... cirrhosis: 3%-20% Renal ... Distal (Type I) renal ... Adenocarcinoma Treatment ... Sjogrens #Syndrome #Rheumatology