10 results
Reduced DOAC Dosing for Atrial Fibrillation 

#DOAC #Reduced #Dosing #Reduction #Dose #Anticoagulation #Pharmacology #AFib #Renal #CKD
Reduction #Dose #Anticoagulation ... #Pharmacology # ... AFib #Renal #CKD
Atrial Fibrillation (A-Fib) Summary

Symptoms:
• Palpitations, light-headedness, dizziness, dyspnea, exercise intolerance, chest pain, near-syncope, syncope.

Why?
Cardiac:
	• Valvular heart
Fibrillation (A-Fib ... control with early Afib ... (< 5% pts with afibb ... Mechanical heart valve ... #Fibrillation #AFib
Stroke Etiologies
Hemorrhagic (IPH, SAH)
Ischemic
 - Large Vessel Atherosclerosis
 - Cardioembolic: Atrial fib, prosthetic valves, LV aneurysm,
Cardioembolic: Atrial fib ... , prosthetic valves ... embolism, Occult a-fib ... Stroke #causes #differential
DOAC: Cheat Sheet - Atrial Fibrillation, VTE Prophylaxis, VTE and Renal Dosing

Renal Dosing:
Apixaban (25% renal clearance):
AFib: CrCl 15-50 ... OralAnticoagulant #Anticoagulation ... #Hematology #Pharmacology
Causes of Ischemic Stroke - Differential Diagnosis Framework
Important to determine and treat the etiology behind because
Ischemic Stroke - Differential ... • Arrhythmias: Afib ... stenosis, Prosthetic valve ... #Stroke #CVA #Differential
Antiplatelet Medications - Summary Table

Aspirin - Inhibits cyclooxygenase, preventing formation of thromboxane A2
 • Acute coronary
inhibitor and anticoagulation ... Alternative to anticoagulation ... in a-fib P2Y12 ... with aspirin and anticoagulation ... Summary #Table #Pharmacology
Endocarditis Summary

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV substance use
• IV catheter
• Recent
• Prosthetic valve ... formation • Other vegetations ... Marantic (NTBE) Differential ... cause + Systemic anticoagulation ... -mm left sided vegetations
Palpitations - Differential Diagnosis Framework

What?
• It is an unpleasant awareness or sensation that the heart is
Palpitations - Differential ... failure • Mitral valve ... Mechanical prosthetic valve ... brain flow (VT/Vfib ... /Afib/WPW) • Loss
Anticoagulant Therapy after PCI (patients with AFib)
Dual-Therapy Preferred:
 • Triple therapy = increased bleeding
(patients with AFib ... Triple #therapy #anticoagulation ... #PCI #pharmacology
Endocarditis - Overview and Differential Diagnosis Framework

Who?
Infectious:
• Pre-existing valvular disease
• Prosthetic valve
• Congenital heart disease
• IV
- Overview and Differential ... formation • Other vegetations ... cause + Systemic anticoagulation ... -mm left sided vegetations ... #Endocarditis #Differential