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diagnosis differential hematology causes algorithm anemia nephrology management workup iron pathophysiology signs symptoms folate folicacid hemolysis high hyperkalemia potassium rbc
Differential diagnosis of schistocytes / fragmentation hemolysis: • Thrombotic microangiopathies (TMA) - TTP
fragmentation hemolysis ... toxin-mediated hemolytic-uremic ... • Severe B12 deficiency ... • Mechanical hemolysis ... anemia" • HELLP
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... DAT (-) → G6PD Deficiency ... → Sickle Cell anemia ... anemia (TTP, HUS ... #Anemia #Differential
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Intravascular Hemolysis ... anemia): ... G6PD deficiency) ... diagnosis #hematology #anemia
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased WBCs - Decreased/NormaI
Causes of Anemia ... Bleed • Hemolysis ... Microangiopathic Hemolytic ... Anemias (MAHA) ... • Early Iron Deficiency
Clinically Important Vitamins and Vitamin Deficiency States Fat-soluble Vitamins: • Vitamin A - Xerophthalmia, night blindness,
Vitamins and Vitamin Deficiency ... • Vitamin E - Haemolytic ... anaemia, ataxia ... #Vitamins #Deficiency ... signs #symptoms #nutrition
Causes of Extravascular and Intravascular Hemolysis - Differential Diagnosis Algorithm Extravascular - Spleen and RES-mediated hemolysis -
Intravascular Hemolysis ... and RES-mediated hemolysis ... Defects • G6PD deficiency ... • PK deficiency ... anemia •
Neurologic Disorders and Associated Nutritional Deficiences That Complicate Bariatric Surgery, According to Time of Onset #Diagnosis
Neurologic Disorders ... and Associated Nutritional ... Deficiences That ... Complications #Nutritional ... #Neurology #NEJM
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Microcytic - Iron-deficiency ... spherocytosis, Hemolytic ... Thalassemia, Iron-deficiency ... cells - G-6-PD deficiency ... Schistocytes - Hemolytic
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV Microcytic (MCV < 80) "TAILS": • Thalassemia
inflammation) • Iron deficiency ... -100): • Non-hemolytic ... , CKD • Hemolytic ... Megaloblastic: Folate deficiency ... , B12 deficiency
Wernicke Encephalopathy - Acute B1 (Thiamine) Deficiency - Diagnosis and Management Diagnosis - Caine Criteria (2 of
upper limb) • Nutritional ... risk factor for nutritional ... deficiency! ... Diagnosis #Management #neurology ... #nutrition
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