9 results
Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
 • Thalassemia
Algorithmic Approach to Anemia ... inflammation) • Iron ... Sideroblastic anemia ... ACD, Aplastic anemia ... MatthewHoMD #Anemia
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Framework for Anemia ... MCV - <80fL - "Microcytic ... " • Iron deficiency ... Megaloblastic: Vitamin B12 ... morphologic #mcv #differential
Micronutrient Deficiencies After Gastric Bypass
Fat-Soluble Vitamins:
 • Vitamin A - Night/complete blindness, xeropthalmia (pathologic dryness of
anemia • Vitamin ... B12 - Macrocytic ... anemia, cognitive ... - Anemia • Zinc ... cognitive dysfunction, anemia
Clinically Important Vitamins and Vitamin Deficiency States
Fat-soluble Vitamins: 
 • Vitamin A - Xerophthalmia, night blindness,
E - Haemolytic anaemia ... paraesthesiae • Folate - Anaemia ... - Anaemia, neurological ... #diagnosis #signs ... #symptoms #nutrition
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
deficiency anemia ... Sideroblastic anemia ... RBC: Vitamin B12 ... deficiency anemia ... RBC #Morphology #differential
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
autoantibodies (pernicious anemia ... anemia, yellow ... wt loss • If anemia ... - CBC, PBS - anemia ... diagnosis #management #nutrition
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
suspected: • Signs ... and symptoms of ... celiac disease • Iron-deficiency ... anemia unresponsive ... microscopic colitis Differential
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
blood cell count (anemia ... anemia DDX: ... • Aplastic Anemia ... Megaloblastic Anemia ... Myelophthisic Anemia
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
- Neurological 12% ... - Hemolytic anemia ... autoantibodies #signs ... #symptoms #mimickers ... #differential #