315 results
diagnosis differential causes hematology algorithm anemia management clinical pathophysiology signs blood symptoms workup microscopy treatment hemolytic path cardiology endocrinology iron
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood Smear ... Megaloblastic Anemia ... cells: Sickle cell disease ... Bite cells: G6PD deficiency ... Peripheral #Blood #Smear
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Normochromic RBCs on Smear ... Reticulocytes • Iron Deficiency ... • B12/Folate Deficiency ... Disease • Marrow ... Spherocytes on Smear
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Normal Blood Smear ... • Dietary Deficiency ... • Pancreatic Disease ... B12 and Folate Deficiency ... • Liver Disease
Hemolytic Anemia - Differential Diagnosis Algorithm Hereditary: • Peripheral blood smear + DAT + further History •
Hemolytic Anemia ... Peripheral blood smear ... DAT (-) → G6PD Deficiency ... → Sickle Cell anemia ... malignancy, autoimmune disease
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Peripheral Smear ... Acute hemolysis, deficiency ... anemia, Rebound ... Vasculitides, IBD, Celiac disease
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... Myeloproliferative Disease ... or folic acid deficiency ... treatments • Copper deficiency ... Peripheral blood smear
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
RBC: Pyridoxine deficiency ... Thalassemia, Iron deficiency ... disease anemia ... B12 or Folate deficiency ... Cell RBC: G6PD deficiency
Elliptocyte - Note the shape of these appropriately named erythrocytes. In addition to hereditary elliptocytosis, elliptocytes can
megaloblastic anemia ... myelophthisic anemia ... and severe iron deficiency ... anemia. ... BloodSmear #Blood #Smear
Hemolytic Anemias - Differential Diagnosis Algorithm Signs of anemia and hemolysis: • ↓ Haptoglobin • ↑ LDH
Hemolytic Anemias ... Algorithm Signs of anemia ... Abnormal peripheral smear ... Autoimmune Hemolytic Anemias ... #Hemolytic #Anemias
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Microcytic - Iron-deficiency ... , Liver diseases ... Thalassemia, Liver diseases ... cells - Renal diseases ... , Liver diseases
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