106 results
Effect of Selected Diseases on Complement Levels - C3, C4
 • SLE C3 ↓ C4 ↓↓
Selected Diseases on Complement ... Levels - C3, C4 • SLE ... • Hereditary angiooedema ... • Infection eg SBE ... ThePeanutKidney #Complement
Quincke's Disease - Isolated Uvula Angioedema

By Dr. Ajay Jain

#Quinckes #Disease #Edema #Uvula #Uvulitis #Angioedema #uvular #clinical
Isolated Uvula Angioedema ... Uvula #Uvulitis #Angioedema ... uvular #clinical #video
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
disease, hereditary angioedema ... Hypocomplementemia #Low #Complement
Facial Swelling from Hereditary Angioedema on Physical Examination

19 year old Hereditary Angioedema (HAE) patient from Turkey.
from Hereditary Angioedema ... old Hereditary Angioedema ... HAE #Hereditary #Angioedema ... #clinical #video
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
fibrinolysis (reduces complement ... w/ hereditary angioedema
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... 90% - Low complement ... Erythematosus (SLE ... are evocative of SLE ... 80% - Low complement
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
anti-GBM) 10%: - Low Complement ... Levels: SLE, Cryoglobulinemic ... Vasculitis - Normal Complement
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE ... are evocative of SLE ... 80% - Low complement ... management of SLE ... Lupusreference #SLE
Systemic Lupus Erythematosus (SLE): Pathogenesis

 • Genetic factors (Mutations in HLA- DR2/HLA-DR3 genes, complement genes, cytokine
Erythematosus (SLE ... HLA-DR3 genes, complement ... self-antigens, activating complement ... Erythematosus #SLE
Complement 1 esterase inhibitor (C1-INH) Deficiency Testing Algorithm
INDICATIONS FOR TESTING:
 • Recurrent angioedema (without urticaria)
 •
Complement 1 esterase ... : • Recurrent angioedema ... family history for angioedema ... ARUPLabs #C1INH #Complement