92 results
Effect of Selected Diseases on Complement Levels - C3, C4
 • SLE C3 ↓ C4 ↓↓
Selected Diseases on Complement ... • Hereditary angiooedema ... ThePeanutKidney #Complement
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
disease, hereditary angioedema ... Hypocomplementemia #Low #Complement
Tranexamic Acid - Indications and Pharmacology
Pharmacokinetics:
 • MOA: Inhibits plasminogen activation to plasmin & inhibits fibrinolysis
fibrinolysis (reduces complement ... w/ hereditary angioedema
Pulmonary Renal Syndromes and Mimics - Differential Diagnosis Framework
Diffuse alveolar hemorrhage + rapidly progressive glomerulonephritis
90%:
 -
Pulmonary Renal ... anti-GBM) 10%: - Low Complement ... Vasculitis - Normal Complement ... Kumfer @AnnKumfer #Pulmonary
Thrombotic Microangiopathies - Primary Thrombotic Microangiopathy (TMA) - Differential Diagnosis Table

 • Thrombotic Thrombocytopenic Purpura (TTP)
Differential Diagnosis Table ... HUS (aHUS) - Complement-mediated
Rapidly Progressive Glomerulonephritis (RPGN)
RPGN has three primary pathophysiologic causes differentiated by immunofluorescence

Immune Complex Mediated (granular staining):
staining): • Low Complement ... Idiopathic • Normal Complement ... With associated pulmonary
Complement 1 esterase inhibitor (C1-INH) Deficiency Testing Algorithm
INDICATIONS FOR TESTING:
 • Recurrent angioedema (without urticaria)
 •
Complement 1 esterase ... : • Recurrent angioedema ... family history for angioedema ... ARUPLabs #C1INH #Complement
Hypoxemia / Hypoxia - Rapid Response Management Algorithm

Stridor - Upper airway pathology:
 • Anaphylaxis
 • Foreign
Foreign body • Angioedema ... pneumonia • Water: pulmonary ... Algorithm #rapid #pulmonary
Characteristics of Important Exudative Pleural Effusions

#Exudative #Pleural #Effusions #Comparison #Table #Characteristics #Differential #Pulmonary
Effusions #Comparison #Table ... #Differential #Pulmonary
Lung Auscultation and Physical Exam Findings in Selected Lung Disorders

#PhysicalExam #Auscultation #Pulmonary #Percussion #Dullness #Fremitus #BreathSounds
#Auscultation #Pulmonary ... Transmitted #Comparison #Table