745 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... - Positive in up ... - Positive in 60 ... - Positive in 60 ... Erythematosus #Diagnosis
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
- Rarely positive ... - Positive in > ... - Positive in up ... - Positive in 60 ... #rheumatology #diagnosis
Rheumatoid Arthritis - 2020 ACR-EULAR Classification
≥ 6 of 10 points = definite RA
Joint Involvement:
Negative RF, negative anti ... RF or low positive ... anti CCP Ab - 2 ... anti CCP Ab - 3 ... Rheumatoid #Arthritis #diagnosis
Medications that Can Cause False Positives on Drug Tests

Urine drug screens (UDSs) are simple to use,
Can Cause False Positives ... yielding false-positive ... can cause false positives ... and ofloxacin • Anti-psychotic ... #differential #diagnosis
Warm Antibody Autoimmune Hemolytic Anemia 
1) DIAGNOSE AIHA
 • Anemia: macrocytic > normocytic, ↑ reticulocytes
 •
Hemolytic Anemia 1) DIAGNOSE ... bilirubin, ↑ LDH • Anti-RBC ... autoantibodies: positive ... → schizocytes, Positive ... Hemolytic #Anemia #diagnosis
Hepatitis B Virus Serology and Interpretation
HBsAg - Anti-HBs - Anti-HBc - HBeAg - Anti-HBe
 - Acute
Interpretation HBsAg - Anti-HBs ... - Anti-HBc - HBeAg ... - Anti-HBe - ... immunity) - False-positive ... Interpretation #diagnosis
Status Epilepticus - Management
Seizure > 5 mins or two seizures without complete recovery between them
PEDS
Benzo Dose
between them PEDS ... Benzo Dose 2 → Anti-epileptic ... #2 → Anti-epileptic ... treatment #algorithm #peds
Important Biostatistics and Epidemiology Equations

Sensitivity = TP / (TP + FN) = true positives / disease
TP + FN) = true positives ... disease absent Positive ... TP + FP) = true positives ... / all positives ... #calculations #diagnosis
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... : - ANCA-positive ... ab, anti-GBM ab ... , ANA, C3, C4, anti-CCP ... #differential #diagnosis
Main types of autoimmune encephalitis in the ICU. 
Anti-NMDAR anti-N-methyl-d-aspartate receptor, ADEM acute disseminated encephalomyelitis, Anti-GFAP
Anti-NMDAR anti-N-methyl-d-aspartate ... anti-glial fibrillary ... anti-gamma aminobutyric ... anti-leucine-rich ... table #neurology #diagnosis