556 results
I’M DAMN SHARP - Lupus Diagnosis Mnemonic
I  	 Immunoglobulins (Anti-dsDNA, Anti-Sm, Anti-phospholipid)
M 	 Malar Rash
D
Immunoglobulins (Anti-dsDNA ... , Anti-Sm, Anti-phospholipid ... Pleuritis) H Hematologic ... erythematosus #rheumatology
Autoimmune Myositis
Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
heliotrope rash, Shaw sign ... , holster sign, ... Around half of anti-SRP ... and anti-HMGCR ... Myositis #diagnosis #rheumatology
Leser–Trélat Sign on Physical Exam

Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy.

#Leser
Leser–Trélat Sign ... paraneoplastic sign ... #LeserTrelat #Sign ... PhysicalExam #clinical #video ... #skin #dermatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
60-70% - Anti-SSA ... 5-10% - Anti- ... 5-15% - Anti-Ku ... autoantibodies #signs ... #differential #rheumatology
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... , Anti-Ro (SSA) ... and Anti-La (SSB ... (SSA), Anti-La ... Autoantibodies #Rheumatology
Inflammatory Myopathies
Dermatomyositis
 • Onset: Subacute
 • Pattern: Proximal
 • CK: Up to 50X ULN
 • Autoantibodies:
, anti-Mi-2, anti-TIF ... -1, anti-NXP-2 ... heliotrope, shawl sign ... , anti-HMGCR • ... diagnosis #comparison #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... shoulders (in a shawl sign ... Inverse Gottron’s sign ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Corrigan's Sign in Severe Aortic Regurgitation

- Dr. Andres S. Kohan https://twitter.com/KohanAndres

#Corrigans #AorticRegurgitation #Pulse #PhysicalExam #Video #Neck
Corrigan's Sign ... #PhysicalExam #Video ... #Neck #Signs #
Positive J-Sign - Maltracking Patella on Knee Physical Exam

The J sign correlates with poor patellar tracking
Positive J-Sign ... Exam The J sign ... #Positive #JSign ... #J #Sign #Knee ... Patella #clinical #video
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
- SLE Anti-histone ... (AMA), Anti-sp100 ... - SLE Anti-SSA ... (Ro), Anti-SSB ( ... diagnosis #table #rheumatology