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diagnosis differential management algorithm clinical neurology nephrology cardiology pharmacology hematology rheumatology table dermatology endocrinology pathophysiology physicalexam video pulmonary pediatrics gastroenterology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
Pulmonary Renal Syndromes ... polyangiitis) Anti-basement ... Pulmonary Renal Syndromes ... Goodpasture's cause ... diagnosis #management #treatment
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... SLE • Mikulicz syndrome ... /SSA & Anti-La/SSB ... Hypocomplementemia • Can cause ... Adenocarcinoma Treatment
Treatment Options for Helicobacter Pylori and Peptic Ulcer Disease Active Helicobacter pylori—associated ulcer 1. Treat with anti—H pylori
Treatment Options ... Treat with anti—H ... Treatment options ... Consider other causes ... Zollinger-EIIison syndrome
Hyperthermia Syndromes Comparison Serotonin Syndrome - NMS - Malignant Hyperthermia - Malignant Catatonia Cause - Onset - Vitals
Hyperthermia Syndromes ... Comparison Serotonin Syndrome ... Malignant Catatonia Cause ... Mental Status - Treatment ... #Hyperthermia #Syndromes
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
Anti-dsDNA (in 70% ... of cases) 2 ... Anti-histone (in ... seen in 30—70% of cases ... • Sjögren syndrome
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
- SLE Anti-histone ... Anticentromere - CREST syndrome ... - SLE Anti-SSA ... La) - Sjogren's syndrome ... Goodpasture's syndrome
Secondary causes of Hypertension • Medications, Drugs, Chemo: NSAIDS, Steroids, CNI, Alcohol, Cocaine, OCP, Licorice, MAOI,
Secondary causes ... Licorice, MAOI, Anti ... Other Endocrine causes ... low renin HTN causes ... #Secondary #causes
Hantavirus Pathogen: Hantavirus - Rodents are the primary reservoir Transmission: • Shed in the urine, feces, saliva of
barns and lake houses ... Cardiopulmonary Syndrome ... • Specific anti-hantavirus ... • Autopsy PCR Treatment ... diagnosis #management #treatment
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
screening test Anti-dsDNA ... block • Sjogren syndrome ... polymyositis overlap syndrome ... ) Anti-Smith - ... severe disease Treatment
Causes of Erythema Nodosum - Mnemonic NO cause found in 60% of cases Drugs (antibiotics e.g., sulfonamides, amoxicillin) Oral
Causes of Erythema ... Mnemonic NO cause ... found in 60% of cases ... Sarcoidosis or Lofgren's syndrome ... Nodosum #Mnemonic #Causes
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