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Summary table of types of hypersensitivity reactions. Type 1 - Mediators: lgE - Antigen Form: Soluble
hypersensitivity reactions ... Mediators: lgE - Antigen ... Form: Soluble antigen ... Acute transfusion reaction ... hypersensitivity #reactions
Hypersensitivity: Definitions • Type I - Production of lgE Abs that bind to harmless allergens and
to an allergic reaction ... against the antigen ... cell surface, and antigen-surface ... to an allergic reaction ... small antibody-antigen
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Penicillin-induced drug reaction ... Immunological Target: Antigen-Ab ... Dermatitis (ie. reaction ... Allergy #Allergic #Reactions
Allergic Rhinitis: Pathogenesis and clinical findings 1. Allergy Sensitization -> Antigen Exposure -> APC (macrophages, HLA class
Sensitization -> Antigen ... class II) process antigen ... Primary Reaction ... Secondary Reaction ... after the primary reaction
Hypersensitivity Types and Their Mechanisms Type I - lgE - Soluble antigen - Allergen-specific lgE antibodies bind
lgE - Soluble antigen ... IgM - Cell-bound antigen ... IgM - Soluble antigen ... - Antigen-antibody ... Allergy #Diagnosis #Reactions
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
Allergic reaction ... Macrophage engulfs antigen ... -> Antigen presentation ... cells recognize antigen
Type II Hypersensitivity: Pathogenesis and clinical findings Definition: When antigens bind to the body's cell surfaces, forming
surfaces, forming an "antigen-surface ... antibody-mediated immune reaction ... Antigen binds receptor ... platelets) -> An "antigen-surface ... against either the antigen
Acute Rheumatic Fever: Pathogenesis and Clinical Findings Delayed autoimmune reaction -> Molecular mimicry -> GAS antigen cross-reacts with host ->
Delayed autoimmune reaction ... mimicry -> GAS antigen
Causes of Interstitial Lung Disease - Differential Diagnosis Algorithm Idiopathic Interstitial Pneumonia • (UIP) Usual Interstitial Pneumonia
hypersensitivity) reaction ... to inhaled antigen
Estimated Incidence of Transfusion Reactions Graphical Depiction of transfusion reactions ordered from most highest to lowest incidence. #Diagnosis
of Transfusion Reactions ... of transfusion reactions ... Transfusion #Consent #Reactions
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