174 results
Hashitoxicosis - Autoimmune thyroid disease overlap syndrome of Graves' and Hashimoto's disease

Autoimmune thyroid disease overlap syndrome
disease overlap syndrome ... disease overlap syndrome ... destruction by cell and antibody-mediated ... • TSH-receptor antibodies ... Endocrinology #Pathophysiology
Nomenclature of Monoclonal Antibodies (-mab)

- Dr. Axel Grothey
@agrothey

#Nomenclature #Monoclonal #Antibodies #Mab #Antibody #Naming
of Monoclonal Antibodies ... Nomenclature #Monoclonal #Antibodies ... #Mab #Antibody
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies)
 • Systemic lupus erythematosus
   1. Anti-dsDNA
ANA (Antinuclear Antibody ... Antineutrophil cytoplasmic antibodies ... anti-topoisomerase antibody ... cases • Sjögren syndrome ... Antineutrophil #antibodies
Autoantibodies and their Disease Associations
ANA - Non-specific; common in SLE, autoimmune hepatitis
Anti-CCP, Rheumatoid factor - RA
Anti-dsDNA
La) - Sjogren's syndrome ... polyangiitis U1-RNP antibody ... disease Endomyseal antibody ... Goodpasture's syndrome ... #rheumatology #antibodies
Estimated Timeline for Detection of SARS-CoV-2 Infection Relative to Symptom Onset

#COVID19 #SARSCOV2 #PCR #Serology #Antibodies #Antibody
PCR #Serology #Antibodies ... #Antibody #Laboratory
Autoantibodies in Rheumatology
 • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
(anti-nuclear antibody ... others (RNP, aPL antibodies ... Antiphospholipid Antibody ... Syndrome: Anti-cardiolipin ... LAC) • Sjogren Syndrome
COVID-19 PCR and Serology Testing - Timeline
 • Nucleic Acid Test - Most reliable and can
first 7 days • Antibody ... PCR #Serology #antibody ... #antibodies #testing
Important Cardiac Transplant Medications and Side Effects
 • Cyclosporine (Sandimmune, generic) - Calcineurin inhibitor, decreasing T
• Polyclonal antibodies ... Antilymphocyte antibody ... • Monoclonal antibodies ... , IL2-receptor antibody ... Antilymphocyte antibody
Type II Hypersensitivity: Pathogenesis and clinical findings
Definition: When antigens bind to the body's cell surfaces, forming
a maladaptive antibody-mediated ... specific pre-formed antibodies ... produce autoimmune antibodies ... entire complex -> Antibody ... Allergy #Immunology #pathophysiology
Type I Hypersensitivity: Pathogenesis and clinical findings
Definition: Production of lgE Antibodies that bind to harmless allergens
Production of lgE Antibodies ... that secrete lgE-antibodies ... creating an allergen-antibody ... -> Allergen-antibody ... Allergy #Immunology #pathophysiology