13 results
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
(AFLP) Three syndromes ... child * Severe cases ... TTPHUS #HELLP #AFLP ... #obstetrics #hematology ... #diagnosis #table
Causes of AKI in Pregnancy - Differential Diagnosis
Creatinine - Platelets - Transaminases - LDH - PT/PTT
Causes of AKI in ... Pregnancy - Differential ... Nephritis • AFLP ... Differential #Diagnosis #Causes ... #table
Thrombocytopenia and Pregnancy
Three syndromes in the critically ill pregnant woman who presents with coagulation defects.
1) HELLP
critically ill pregnant ... child * Severe cases ... TTPHUS #HELLP #AFLP ... Obstetrics #OBGyn #Hematology ... Diagnosis #Comparison #Table
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Wilson's • Pregnancy ... - AFLP, HELLP ... Others #LFTs #Hepatology ... Diagnosis #Algorithm #Causes
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase (ALP ... - Increased ALP ... Intestine - Other causes ... - Drugs - Pregnancy ... Diagnosis #Algorithm #hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Fatty Liver of Pregnancy ... (AFLP) Pathophysiology ... = nonspecific (nausea ... iMedEducation #AFLP ... #hepatology #obstetrics
Causes of Thrombocytopenia - Differential Diagnosis Framework
Decreased Production:
 - Drugs (chemo, yang, sulfa, acetaminophen, NSAIDs, quinine,
Causes of Thrombocytopenia ... DIC, TTP, HUS - Antibody-mediated ... antiphospholipid syndrome - Pregnancy ... Diagnosis #Framework #hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
almost) all TMAs cause ... drug-associated TMA (antibody ... transplant, infection, pregnancy ... Microangiopathy #TMAs #hematology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... melanoma, myeloma • Pregnancy ... • AST/ALT > ALP ... disease - If ALP ... diagnosis #algorithm #hepatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... Discontinuation of causal ... versus DIL • Laboratory ... sle #comparison #table ... #rheumatology #