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diagnosis differential anemia management classification comparison sle algorithm erythematosus hemolysis aflp arthritis criteria druginduced hellp obstetrics pregnancy systemic testing thrombocytopenia
Laboratory Testing in Hemolytic Anemia Intravascular vs Extravascular Hemolysis Reticulocytes Unconjugated bilirubin LDH Peripheral smear Haptoglobin Urine hemosiderin Urine hemoglobin Carboxyhemoglobin #Hemolytic #Anemia #Laboratory #Testing #workup
Laboratory Testing ... in Hemolytic Anemia ... #Anemia #Laboratory ... #Testing #workup ... #diagnosis #hematology
SLICC SLE Diagnostic Criteria - Systemic Lupus Erythematosus Clinical and Immunologic Criteria CLINICAL CRITERIA - ACUTE CUTANEOUS LUPUS
NEUROLOGIC - HEMOLYTIC ... ANA level above laboratory ... level above laboratory ... the absence of hemolytic ... #Diagnosis #Rheumatology
Causes of Hemolytic Anemia - Differential Diagnosis Inherited • Membrane • Internal - Hemoglobin
Causes of Hemolytic ... Membrane - Antibody ... Sophia_Hayes_MD #Hemolytic ... Differential #Diagnosis #Causes ... #hematology
Warm Antibody Autoimmune Hemolytic Anemia 1) DIAGNOSE AIHA • Anemia: macrocytic > normocytic, ↑ reticulocytes •
Warm Antibody Autoimmune ... Hemolytic Anemia ... 2) LOOK FOR a cause ... Pouchelon #Warm #Antibody ... management #treatment #rheumatology
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Algorithm and Causes ... #Hemolytic #Anemia ... #Differential #Causes ... #Workup #Hematology
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus Clinical Domains: • Constitutional domain: Fever • Cutaneous domain: Non-scarring
pericarditis • Hematologic ... Thrombocytopenia, Autoimmune hemolysis ... Antiphospholipid antibody ... , Anti-Sm antibody ... Erythematosus #diagnosis #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Framework for Hemolysis ... Extravascular Causes ... usually IgG) (e.g. lupus ... Extravascular #Causes ... differential #diagnosis #hematology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... (anti-nuclear antibody ... Autoantibodies #Rheumatology ... #associations #table
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Diseases: • Systemic lupus ... hemoglobinuria • Antibody-mediated ... hemolysis Nutritional ... Differential #Diagnosis #Hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
calcium-b) • Laboratory ... • Immunologic Workup ... • Immunologic Workup ... sle #comparison #table ... #rheumatology #
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