38 results
Spectrum of activity for systemic antifungal agents
Antifungals: 5FC, flucytosine; AMB, amphotericin B; ANI, anidulafungin; CAS, caspofungin;
activity for systemic antifungal ... agents Antifungals ... .2015.10.012 #Antifungal
Antifungal Coverage Activity Antibiogram 

Spectrum of action of systemic antifungal agents. Solid blocks represent species in
Antifungal Coverage ... action of systemic antifungal ... species in which the antifungal ... PMC3146381/ #Antifungal
Common toxicities of antifungal agents. 
CNS = central nervous system; 5-FC = flucytosine; GI = gastrointestinal;
toxicities of antifungal ... #antifungal #toxicities
Antifungal Agents Frequently Used in Leukemia
Antibiogram:
 • Fluconazole
 • Itraconazole
 • Voriconazole
 • Posaconazole
 • Caspofungin
Antifungal Agents ... @ZhuoerXie #Antifungal
Rare Invasive Yeasts - Species and Antifungal Therapy

Cryptococcus, 
Geotrichum, 
Kodamaea, 
(Pichia)ohmeri, 
Malassezia, 
Pseudozyma, 
Rhodotorula, 
Saccharomyces, 
Saprochaete
- Species and Antifungal ... Invasive #Yeasts #Antifungal
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview

Mechanism: binds ergosterol in membrane and
Antifungal Polyenes ... Overview #Polyenes #Antifungal
Antifungal Azoles - Antibiotics Class Overview

Mechanism:  inhibit ergosterol synthesis (important component of fungal cell membranes)
Antifungal Azoles ... Overview #Azoles #Antifungal
Invasive Candidiasis (IC)

Diagnosis:
Culture:
 • Gold standard, but Slow (~2-3 days), 50% sensitivity
 • Blood Sample
 •
Tests Conduct antifungal ... Candidiasis #IC #antifungal
Antifungal Organ System Tissue Penetration

Concentrations in tissues and body fluids for each systemic antifungal agent relative
Antifungal Organ ... each systemic antifungal ... #Antifungal #OrganSystem
Antifungal Echinocandins  - Antibiotics Class Overview

Mechanism: Inhibit glucan synthesis in fungal cell wall by blocking
Antifungal Echinocandins ... Echinocandins #Antifungal