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IDSA Recommendations for Treating Mucosal Candidiasis in HIV-AIDS Oropharyngeal Candidiasis: Initial Episodes (Duration of Therapy: 7–14 days) Preferred
Treating Mucosal Candidiasis ... Oropharyngeal Candidiasis ... Note: Systemic antifungals ... of esophageal candidiasis ... infections #HIVAIDS #pharmacology
Spectrum of activity for systemic antifungal agents Antifungals: 5FC, flucytosine; AMB, amphotericin B; ANI, anidulafungin; CAS, caspofungin;
activity for systemic antifungal ... agents Antifungals ... .2015.10.012 #Antifungal ... antibiogram #management #pharmacology
Invasive Candidiasis (IC) Diagnosis: Culture: • Gold standard, but Slow (~2-3 days), 50% sensitivity • Blood Sample •
Invasive Candidiasis ... Tests Conduct antifungal ... #Invasive #Candidiasis ... #IC #antifungal
Common toxicities of antifungal agents. CNS = central nervous system; 5-FC = flucytosine; GI = gastrointestinal;
toxicities of antifungal ... #antifungal #toxicities ... SideEffects #Adverse #Pharmacology
Antifungal Coverage Activity Antibiogram Spectrum of action of systemic antifungal agents. Solid blocks represent species in
Antifungal Coverage ... action of systemic antifungal ... species in which the antifungal ... PMC3146381/ #Antifungal ... Echinocandins #Pharmacology
Tinea Versicolor (Pityriasis versicolor) NOT a dermatophyte infection Caused by saprophytic, lipid-dependent yeasts Clinical •
Management • Topical antifungals ... • Oral antifungal
Antifungal Agents Frequently Used in Leukemia Antibiogram: • Fluconazole • Itraconazole • Voriconazole • Posaconazole • Caspofungin
Antifungal Agents ... @ZhuoerXie #Antifungal ... #antibiogram #pharmacology
Antifungal Polyenes - Amphoterecin B, Abelcet, Ambisome - Antibiotics Class Overview Mechanism: binds ergosterol in membrane and
Antifungal Polyenes ... #Pharmacology #Antibiotics ... Overview #Polyenes #Antifungal
Antifungal Azoles - Antibiotics Class Overview Mechanism: inhibit ergosterol synthesis (important component of fungal cell membranes)
Antifungal Azoles ... Isavuconazole(PO or IV) #Pharmacology ... Overview #Azoles #Antifungal
Oral Cavity Lesions in a patient with HIV/AIDS White plaque - Pseudo-membranous candidiasis - Oral hairy leukoplakia
Pseudo-membranous candidiasis ... - Erythematous candidiasis
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