23 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
of Old and New Potassium-Binding ... edgarvlermamd #Potassium ... Comparison #Table #Pharmacology ... #HyperKalemia #Nephrology
Hyperkalemia: Diagnostic algorithm
Decreased renal potassium excretion
 • Acute renal failure
 • Chronic renal failure
 • Drugs
Increased
Decreased renal potassium ... Drugs Increased potassium ... Diabetic Nephropathy Renin ... Normal, Renin High ... Diagnosis #algorithm #nephrology
Drugs that Impair Renal Potassium Excretion 

Decreased ENaC channel function: Amiloride, Triamterene, Pentamidine
Decreased Aldosterone Synthesis: Heparin,
that Impair Renal Potassium ... ARBs Decreased Renin ... Pathophysiology #Pharmacology ... #Impaired #Potassium
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Metolazone) 5) Potassium-sparing ... nephron #diuretics #pharmacology ... #nephrology #medications
Here’s a review of the Renin-Angiotensin-Aldosterone system (RAAS)

This is a very common pathway that clinicians should
review of the Renin-Angiotensin-Aldosterone ... with excreting potassium ... will increase potassium ... ReninAngiotensinAldosteroneSystem #RAAS #Pharmacology ... #Renin #Angiotensin
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Hyperkalemia • Direct renin ... Aliskiren) • Renin ... pathophysiology #pharmacology ... #potassium #medications
Differentiating Benign Paroxysmal Positional Vertigo (BPPV) From Vestibular Neuritis-Labyrinthitis
BENIGN PAROXYSMAL POSITIONAL VERTIGO
 • Age: More common
Differentiating Benign ... Neuritis-Labyrinthitis BENIGN ... ) • Epley maneuver ... saccade seen) • Epley ... Labyrinthitis #diagnosis #neurology
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Chlorthalidone POTASSIUM-SPARING ... #Medications #Pharmacology ... summary #table #nephrology
Hypokalemia Evaluation Algorithm

Before evaluating hypokalemia, life threatening complications such as arrhythmias and paralysis should be looked
treated with IV potassium ... Pressure: - ↑ Renin ... tumor - ↓ Renin ... #differential #potassium ... #nephrology #low
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
the basis of the potassium-to-creatinine ... blood volume • ↑ Renin ... artery stenosis, Renin ... hypokalemia #urine #potassium ... algorithm #diagnosis #nephrology