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diagnosis algorithm anemia hemolysis hemolytic adrenalmass causes hepatitis hepatology injury liver agglutinin aiha antiglobulin atlas benign bloodcell cold dat dermatology
Autoimmune Hemolytic Anemia (AIHA) - Differential Diagnosis Table Warm AIHA (48-70%) Cold AHA (16-32%) • Donath-Landsteiner HA (paroxysmal
Autoimmune Hemolytic ... Anemia (AIHA) - Differential ... Donath-Landsteiner HA (paroxysmal ... MatthewHoMD #Autoimmune ... Diagnosis #Table #hematology
Expected DAT Results in Autoimmune Hemolysis DAT Negative Hemolysis • DAT Poly ( - ), IgG (
DAT Results in Autoimmune ... , C3d ( +/- ) Paroxysmal ... #antiglobulin #test ... #DAT #Autoimmune ... #Hemolysis #hematology
Pancytopenia - Differential Diagnosis Congenital Diseases: • GATA2 deficiency • Fanconi’s anemia • Wiskott-Aldrich syndrome • Ribosomopathy or telomeropathy Cancer: • Leukemia • Lymphoma Inflammatory
Pancytopenia - Differential ... Inflammatory and Autoimmune ... erythematosus • HLH • Paroxysmal ... #Pancytopenia #Differential ... #Diagnosis #Hematology
Benign Adrenal Mass - Differential Diagnosis Algorithm Hyperplasia - Often Bilateral • Congenital Adrenal Hyperplasia • ACTH
Adrenal Mass - Differential ... Dexamethasone Suppression Test ... Pheochromocytoma (Paroxysmal ... AdrenalMass #Benign #Differential ... Diagnosis #Algorithm #Endocrinology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Transfusion reaction, Paroxysmal ... Immune-mediated: - Autoimmune ... idiopathic) - Autoimmune ... Extravascular #Causes #differential ... #diagnosis #hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Membrane): - Autoimmune ... Laboratory Tests ... #Hemolysis #Differential ... #Diagnosis #hematology
Malignant Adrenal Mass - Differential Diagnosis Algorithm Suggestive of Malignancy: Inhomogenous Density, Delay in CT Contrast Washout
Adrenal Mass - Differential ... Dexamethasone Suppression Test ... Pheochromocytoma (Paroxysmal ... AdrenalMass #Malignant #Differential ... Diagnosis #Algorithm #Endocrinology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral infection, autoimmune ... younger pts) Differential ... macroglobulinemia Paroxysmal ... • Diagnostic Test ... hemolytic #anemia #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
spherocytosis, Autoimmune ... Agglutinate: Cold autoimmune ... hemolytic anemia, Paroxysmal ... RBC #Morphology #differential ... #diagnosis #hematology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Liver Injury - Differential ... Injury → liver test ... Other: NAFLD, Autoimmune ... Liver #Injury #Differential ... #Diagnosis #hepatology
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