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differential management hematology causes liver rheumatology ascites chronic injury lfts acute anemia gastroenterology transaminitis workup aih antibodies celiac hepatopulmonary pancytopenia
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Inflammation - Hepatitis ... Schistosomiasis - Autoimmune ... (Budd-Chiari syndrome ... 14 percent) #Diagnosis ... #Differential #Hepatology
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 Hepatomegaly - Differential Diagnosis Algorithm Malignant • Primary Carcinoma • Metastases • Lymphoma • Leukemia • Polycythemia
Hemochromatosis • Wilson's Disease ... • Budd-Chiari Syndrome ... • Autoimmune ... Primary Biliary Cirrhosis ... #Hepatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
common in SLE, autoimmune ... hepatitis Anti-CCP ... microsomal) - Autoimmune ... Primary biliary cirrhosis ... #diagnosis #table
Ascites - Differential Diagnosis Chronic liver disease (cirrhosis or chronic hepatitis) - 80% Underlying malignancy - 10% Congestive heart
- Differential Diagnosis ... Chronic liver disease ... hepatitis) - 80% ... Fitz-Hugh-Curtis syndrome ... #hepatology
Primary Biliary Cirrhosis - Diagnosis Algorithm Symptoms: Fatigue, Pruritus, Right upper quadrant discomfort Signs: Jaundice, Xanthelasmata, Hepatomegaly Associated history:
Primary Biliary Cirrhosis ... - Diagnosis Algorithm ... disease (e.g. dryness ... #Diagnosis #Algorithm ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
• Ischemia • Autoimmune ... • Cholestatic disease ... • Alcoholic hepatitis ... Infiltrative • Cirrhosis ... Others #LFTs #Hepatology
Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
- Differential Diagnosis ... Metabolic: Wilson Disease ... • Autoimmune ... hepatitis • Iatrogenic ... #causes #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
- Differential Diagnosis ... Other: NAFLD, Autoimmune ... obstruction, HELLP Syndrome ... Causes #Acute #algorithm ... #hepatology
Suspected Celiac Disease - Diagnosis Algorithm Celiac disease suspected: • Signs and symptoms of celiac disease •
- Diagnosis Algorithm ... unresponsive to treatment ... thyroiditis, hepatitis ... • Autoimmune ... #Diagnosis #Algorithm
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
Injury → liver test ... • Infections: Hepatitis ... Other: NAFLD, Autoimmune ... HELLP, Celiac disease ... #hepatology #algorithm
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