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hematology management leukemia differential disorders hemeonc hemophagocytic hlh hodgkins lymphohistiocytosis lymphoma rheumatology activation apml blood cancer chronic cml comparison differentiation
Map of proliferative blood disorders. By Ariella Coler-Reilly @ariellastudies #Algorithm #classification #proliferative #blood #disorders #leukemia #hematology #oncology
ariellastudies #Algorithm ... #classification ... disorders #leukemia #hematology ... #oncology #diagnosis ... #CML #CLL #AML
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... develop leukostasis syndrome ... • Tumor lysis syndrome ... Lymphadenopathy • HSM • Fevers ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Lymphadenopathy • Fevers ... microglobulin Treatment ... #workup #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
- Pel-Ebstein fever ... translocation • Types: Classification ... Malignancies (eg CML ... , ALL) • Solid ... NonHodgkins #comparison #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... • Induce blast cell ... Subacute-Acute: • Common: fever ... #APML #diagnosis ... #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... Algorithm Hodgkin ... Responsive to Treatment ... relapse - Amy ... Lymphoproliferative #Disorders #Classification
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... transformation to AML ... Myelogenous Leukemia (CML ... #diagnosis #hematology ... #oncology
Summary of Oncologic Emergencies Neutropenic fever: - Fever + ANC < 500 → start cefepime ± vancomycin (if
Summary of Oncologic ... : - Fever + ANC ... ± tocilizumab; call ... : - Seen with AML ... #HemeOnc #Diagnosis
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
general feeling of ill ... Leukemia cutis Diagnosis ... Treatment: - Systemic ... #diagnosis #dermatology ... #oncology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Liver function tests ... 5000 to 10,000 ng/mL ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
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