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hematology lupus oncology syndrome causes criticalcare differential druginduced sle summary adultonset algorithm anemia apml barre classification coagulation comparison crystalloids dermatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Erythematosus (SLE) - Diagnosis ... of SLE versus DIL ... - CRP: Usually normal ... life-threatening • Treatment ... #rheumatology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Differential Diaqnoses ... MAS, Visceral, DIC ... Stills #Disease #diagnosis ... #management #treatment ... #rheumatology
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management ... JAK2 mutation OR Abnormally ... transformation into AML ... #Management #Summary ... #treatment #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
+ Bleeding Treatment ... - APTT < 1.5 x normal ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
CRP - Usually normal ... constitutional symptoms • Treatment ... #rheumatology # ... diagnosis #treatment ... #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
that are poorly formed ... Pinpoint-sized red spots ... with isolated del ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
There are similarities and differences between these 3 conditions which all carry treatment implications. Each mimic
carry treatment ... breakdown of glycogen stores ... #diagnosis #differential ... #algorithm #management ... #foamed
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... Renal Failure Treatment ... 500 mg QD until normal ... #management #hematology
The crusade against “Ab”Normal Saline continues. This is a non-physiologic fluid that can harm our
crusade against “Ab”Normal ... Normal saline has ... #foamed #criticalcare ... #management #diagnosis ... #treatment #pharmacology
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