52 results
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... • Pernicious Anemia ... Myelodysplastic Syndromes ... #Macrocytic #Anemia ... Algorithm #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas
 • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Iron-deficiency anemia ... Myelodysplastic syndrome ... PD deficiency, Pulmonary ... Hemolytic uremic syndrome ... #differential #hematology
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary
myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... marrow) -dys- (abnormal ... cytopenias (usually anemia ... Myelodysplastic #Syndrome ... #treatment #hematology
Dyspnea - Differential Diagnosis Framework

Cardiovascular Causes of Dyspnea:
 • Myocardium:
	- Heart failure
	- CAD/ACS
	- Valvulopathy
 • Electrical:
	-
- Tamponade Pulmonary ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... : - Anemia • ... diagnosis #causes #pulmonary
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... (MDS) (normal or ... megakaryocytes and a normal ... #oncology #hematology ... #diagnosis #management
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Framework for Anemia ... thalassemia • Anemia ... some patients) Normal ... Myelodysplastic syndrome ... diagnosis #causes #hematology
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Iron Deficiency Anemia ... athletic training, Pulmonary ... Gastrectomy, WHDA syndrome ... Iron #Deficiency #Anemia ... Algorithm #ferritin #hematology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Bandemia Overview ... • Abnormal temperature ... bacteremia • Abnormal ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Hemolysis - Differential Diagnosis Framework

1) Environment
  - Fragmentation
  - MAHA: TTP, HUS, DIC, HELLP
Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell anemia ... Blood Smear ↑ abnormal ... Differential #Diagnosis #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
number and appears abnormal ... cell types are abnormal ... low and appear abnormal ... cells might look abnormal ... #diagnosis #hematology