14 results
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
to Evaluate an Abnormal ... APTT Step 1: Is ... the PT or APTT ... Prolonging the PT ... ISNeducation #Abnormal
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Investigation of Abnormal ... Tests - Prolonged PT ... - Prolonged aPTT ... and Prolonged PT ... #Coagulation #Abnormal
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged PT ... • Prolonged PT ... (INR), Normal PTT ... , Normal PT (INR ... , Normal PT (INR
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... PT and/or aPTT ... Prothrombin Time (PT ... Jcortesizaguirr #Abnormal ... #PT #aPTT #Prolonged
Approach to Thrombotic Microangiopathy (TMA) - Differential Diagnosis and Management Algorithm

Suspected TMA: Unexplained thrombocytopenia + MAHA
antiglobulin test, PT ... /aPTT MAHA likely ... hemosiderin • PT ... /aPTT normal
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
for a Prolonged PT ... and aPTT If the ... PT and the aPTT ... amyloidosis #Abnormal ... #PT #aPTT #Prolonged
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
PT/NORMAL PTT: ... PT/ABNORMAL PTT ... PT/NORMAL PTT: ... • Acute DIC ABNORMAL ... PT/ABNORMAL PTT
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
Clotting tests can be abnormal ... an inhibitor of normal ... to have 50% of normal ... Plasma → Recheck abnormal ... PT and/or aPTT)
Von Willebrand Disease - Most common inherited bleeding disorder 
Clinical 
 • Easy bruising 
 •
Laboratory • Normal ... type 2B) • Normal ... PT/INR • Normal ... aPTT (prolonged
ISTH Scoring System for Disseminated Intravascular Coagulation (DIC)
Platelet count:
 • Expected: Low (or normal)
 • Elevation
Expected: Low (or normal ... platelet aggregation PT ... , aPTT: • Expected ... factors, Can be normal ... using INR use PT