8 results
Diuretics sites of action on the nephron
1) Acetazolamide (carbonic anhydrase inhibitor)
2) Osmotic diuretics (e.g. mannitol)
3) Loop
Diuretics sites ... . mannitol) 3) Loop ... Metolazone) 5) Potassium-sparing ... #pharmacology # ... nephrology #medications
Summary of Diuretic Agents 
Subclass, Drug, Mechanism of Action, Effects, Clinical Applications, Pharmacokinetics, Toxicities, Interaction
CARBONIC ANHYDRASE
Summary of Diuretic ... empagliflozin LOOP ... Chlorthalidone POTASSIUM-SPARING ... #Medications #Pharmacology ... summary #table #nephrology
Diuretics - Pharmacology

Thiazides diuretics:
 • Inhibit Na+ Cl- cotransporter in distal tubule
 • Chlorothiazide, Chlorthalidone, Indapamide,
Diuretics - Pharmacology ... Metolazone Loop ... Piretanide Potassium ... #Pharmacology # ... nephrology #conversion
Hypokalemia - Differential Diagnosis Algorithm

Transcellular Shift:
 • Alkalosis
 • ↑ beta-2 adrenergic simulation 
 • Erythropoiesis
Differential Diagnosis Algorithm ... intake (anorexia, dementia ... • Discontinued diuretic ... #nephrology #low ... #potassium
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Differential Diagnosis Algorithm ... • HTN Absent: Loop ... and thiazide diuretics ... #causes #potassium ... #low #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Algorithm for patients ... High Urine Cl - Loop ... diuretics, Thiazide ... diuretics, Mg2+ ... #diagnosis #nephrology
Causes of Hypokalemia - Differential Diagnosis Algorithm
Defining the cause of hypokalemia starts by measuring urinary K
Differential Diagnosis Algorithm ... Clinicians should also look ... Post-hypercapnia • Diuretics ... #causes #nephrology ... #potassium
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Urinary Chloride Algorithm ... Remote use of loop ... or thiazide diuretics ... pressure: Active diuretic ... of sodium and potassium