104 results
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Night sweats • Arthralgias ... purpura: Strong sign ... , weight loss, arthralgia ... pulse deficits vascular ... tract, and often causes
Faget Sign - Pulse-Temperature Dissociation
Causes of Relative Bradycardia
 • Infectious Causes: Legionella, Psittacosis, Q fever, Typhoid
Faget Sign - Pulse-Temperature ... Dissociation Causes ... • Infectious Causes ... Non-Infectious Causes ... 30048576/ #Faget #Sign
Faget's Sign & Liebermeister's Rule
Pulse-Temperature Dissociation
EVERY 1 F RISE IN TEMPERATURE -> HR INCREASES 8-10 BPM
INFECTIOUS
Faget's Sign & Liebermeister's ... BPM INFECTIOUS CAUSES ... OTHER CAUSES ... #Fagets #Sign #Pulse ... #differential #causes
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic Fever ... inflammation • Fever ... • Arthralgia ... Pancarditis and valvular ... pathophysiology #diagnosis #signs
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Deposition - Arthralgia ... trabecular thinning -> Avascular ... Myopathy (Also caused ... pathophysiology #signs
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
pharyngeal erythema, fever ... pharyngeal erythema, fever ... endotoxin induces vascular ... Sudden onset of fever ... skin lesions -> Vesicular
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
vomiting • Fatigue Signs ... • Low-grade fever ... Back pain • Arthralgia ... Cortisol Deficiency: Signs ... Reduced libido • Signs
Hypothyroidism – symptoms and signs.

Symptoms: 
Tiredness/malaise, 
Weight gain,
Anorexia,
Cold intolerance, 
Poor memory,
Change in appearance, 
Depression, 
Poor libido,
– symptoms and signs ... coarse skin, Arthralgia ... , Deafness Signs ... Myotonia, Muscular ... Hypothyroid #Features #Signs
Clinical Manifestations of Serotonin Syndrome
 • Ophthalmologic: Mydriasis, Ocular clonus (slow horizontal movements)
 • Gastrointestinal: Diarrhea,
Cardiovascular and vital sign ... : Tachycardia, Fever ... Clonus (inducible), Muscular ... Symptoms #spectrum #signs
Lyme Disease: Early and Late Clinical manifestations
Stage 1. Localized
 • EM appears 7-14 days at the
Fatigue, myalgia, arthralgia ... , headache, fever ... Disease #diagnosis #signs