21 results
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic Fever ... • Arthralgia ... RheumaticFever #pathophysiology ... #diagnosis #signs ... #symptoms #complications
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
endotoxin induces vascular ... hemorrhagic rash; symptoms ... skin lesions -> Vesicular ... non-specific viral symptoms ... peds #pediatrics #pathophysiology
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Deposition - Arthralgia ... trabecular thinning -> Avascular ... Myopathy (Also caused ... Complications #pathophysiology ... #signs #symptoms
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... within morulae Signs ... and symptoms: ... after bite • Fever ... ), cough (30% cases
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
vomiting • Fatigue Signs ... • Low-grade fever ... Back pain • Arthralgia ... Cortisol Deficiency: Signs ... Reduced libido • Signs
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
• CT: Halo sign ... Constitutional symptoms ... Legionella: • Nausea ... factor • May cause ... ), anemia, arthralgia
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Episcleritis Signs ... and Symptoms: ... (arthritis and arthralgia ... development of skin symptoms ... Causes: - Idiopathic
Uncommon Causes of Noncardiogenic Pulmonary Edema (NCPE) - Differential Diagnosis Framework

High Altitude Pulmonary Edema:
 • Accumulation
- Low-grade fever ... insufficiency, fever ... • Signs/Symptoms ... • Signs/Symptoms ... - The classic signs
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
survival is 93-95% Pathophysiology ... General: fever, ... syndrome: ACUTE, fever ... presentation with fever ... Diagnosis #Management #Signs
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... - 80% have fever ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology