35 results
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic ... Fever: Pathogenesis ... inflammation • Fever ... • Arthralgia ... pathophysiology #diagnosis #signs
Fever Patterns - Differential Diagnosis Framework

Continuous Fever:
Temp > 38°C with only 1 degree fluctuation in 24
pneumonia • Acute ... infections • Acute ... Non-Infectious Causes ... Brucellosis Faget's Sign ... abscess • Sub-acute
Measles (Rubeola) 
Clinical 
 • High fever 
 • Cough, Coryza, Conjunctivitis (The 3 C's)
Clinical • High fever ... Pneumonia (most common cause ... rnortality) • Acute ... Features #Symptoms #Signs
Lyme Disease: Early and Late Clinical manifestations
Stage 1. Localized
 • EM appears 7-14 days at the
Fatigue, myalgia, arthralgia ... , headache, fever ... • Heralded by neurologic ... Remitting, chronic • Neurologic ... Disease #diagnosis #signs
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
• Meningeal signs ... Systemic symptoms and signs ... (e.g., fever, myalgia ... arteritis • Acute ... #neurology #PHANTOMS
Causes of Dizziness - Vertigo - Differential Diagnosis Algorithm
True Vertigo - Illusion of Rotary Movement
Peripheral Vestibular
Causes of Dizziness ... Differential Diagnosis Algorithm ... symptoms/signs, ... Glomus Tumors - Vascular ... #Causes
Algorithmic Approach to Acute Interstitial Nephritis
When to suspect AIN? (not sensitive)
 • AKI, AKD, rapidly progressive
Algorithmic Approach ... to Acute Interstitial ... triad (<10%): fever ... MatthewHoMD #Acute ... #nephrology #diagnosis
Diseases of the Biliary Tract
Asymptomatic gallstones - Asymptomatic
Symptomatic gallstones - Biliary pain
Cholesterolosis of gallbladder - Usually
Adenomyomatosis - May cause ... gallbladder cancer Acute ... , vomiting, fever ... , Murphy sign Chronic ... pain, jaundice, fever
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
aldosterone Causes ... : Most Common Causes ... Tuberculosis: can cause ... • Low-grade fever ... Back pain • Arthralgia
Acute Kidney Injury - AKI Workup Algorithm and Differential Diagnosis
Baseline Investigations: full blood count with differential,
Acute Kidney Injury ... - AKI Workup Algorithm ... osmolarity If cause ... clinical context and signs ... #causes