29 results
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Acute Rheumatic Fever ... inflammation • Fever ... • Arthralgia ... RheumaticFever #pathophysiology ... #diagnosis #signs
Practical Pediatric Viral Rash Algorithm

Child presenting with rash and current/ recent symptoms of viral illness but
Practical Pediatric ... Viral Rash Algorithm ... but is well with fever ... five days and no signs ... #Pediatrics #Peds
The Febrile Child - some diagnostic clues to evaluating the febrile child.

#Febrile #Fever #Evaluation #Assessment #Signs
some diagnostic clues ... #Febrile #Fever ... Evaluation #Assessment #Signs ... Diagnosis #Peds #Pediatrics
Systemic Lupus Erythematosus (SLE): Musculoskeletal Manifestations

 • Immune Complex Deposition
    - Arthralgia, Arthritis
Deposition - Arthralgia ... Myopathy (Also caused ... Erythematosus #SLE #MSK ... Complications #pathophysiology ... #signs #symptoms
Epiglottitis - Swollen inflamed epiglottis 
Clinical (Rapid onset) 
 • Fever 
 • Sore throat
Rapid onset) • Fever ... #Epiglottitis #Signs ... #Causes #Diagnosis ... Differential #Peds #Pediatrics
Childhood Immunization Schedule: Why we immunize
 • Diphtheria Toxin -> URT inflammation causes pseudomembrane with hardened
pharyngeal erythema, fever ... endotoxin induces vascular ... skin lesions -> Vesicular ... Immunization #peds #pediatrics ... #pathophysiology
Anaplasma Infection - Anaplasma phagocytophilum
Pathophysiology: 
 • Obligate, intracellular bacteria
 • Transmitted via blacklegged tick —
phagocytophilum Pathophysiology ... within morulae Signs ... after bite • Fever ... is rare (< 10% cases ... ), cough (30% cases
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic Algorithm ... Pathophysiology ... Ill-appearing, vital sign ... instability - New-onset fever ... Color #Targetoid #Algorithm
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Tuberculosis: can cause ... vomiting • Fatigue Signs ... • Low-grade fever ... Back pain • Arthralgia ... Reduced libido • Signs
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
• CT: Halo sign ... Legionella: • Nausea ... factor • May cause ... reported in 100% of cases ... ), anemia, arthralgia